Secretary of State Marco Rubio leaves for his first overseas trip as the nation’s top diplomat on Saturday. Rubio's first stop on the six-day visit is Panama as he sets out on pursuing President Donald Trump’s geopolitical agenda.

Trump used his inaugural address to proclaim his intent to "take back" the Panama Canal, and in a call with reporters on Friday, Special Envoy for Latin America Mauricio Claver-Carone said Rubio’s chief purpose of the trip would be in re-establishing a "Golden Age" for America.

"This trip signifies… that era of American greatness and the Golden Age," he said, adding that "the 21st century will also be an American century."

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Claver-Carone pointed out that Rubio’s trip to Latin America is the first time a secretary of state has traveled to the region as their first official visit abroad in over 100 years. 

"Last time that happened, I believe, was in 1912, when Philander Chase Knox went to Panama… to oversee the conclusion of the Panama Canal’s construction and operations," he told reporters. "What a great message to harken back to that Golden Age of the Americas, as President Trump himself has mentioned."

Rubio is scheduled to meet with Panamanian President José Raúl Mulino.

The pair are expected to discuss migration, combating drug trafficking and China’s presence in the Panama Canal, which Rubio and Trump have argued has become overrun by Chinese companies operating at either end of the crucial waterway.

The Trump administration has argued that the Chinese Communist Party’s (CCP) tight grip over all Chinese companies means that, in extension, the CCP is operating out of the canal and could, in theory, close it to U.S. trade if it chose to — posing a significant security threat. 

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Mulino has repeatedly denied that Chinese companies have any influence over the operations of the Panama Canal, and on Thursday said he would not be negotiating ownership of the canal with Rubio.

"It’s impossible, I can’t negotiate," Mulino said during a Thursday press conference when asked about negotiating control of the canal, The Associated Press reported. "That is done. The canal belongs to Panama."

Mulino apparently claimed confusion over control of the canal was attributed to his predecessor, who severed ties with Taiwan and established diplomatic relations with China in 2017, eventually allowing a Hong Kong consortium to operate ports at both ends of the canal.

Panama maintains that it controls the canal.

Claver-Carone argued that Chinese companies control "everything from force and logistics to telecommunications, infrastructure, and otherwise," which he said is not only a security threat to U.S. interests in the canal, but to the national security of Panama and the Western Hemisphere.

Rubio is also slated to visit El Salvador, Costa Rica, Guatemala and the Dominican Republic, where he will meet with the presidents of each nation before returning to the U.S. on Thursday. 

Addressing Chinese influence in these countries, along with gang violence, migration and drug trafficking, will also be top of Rubio’s agenda.

Secretary of State Marco Rubio paused all U.S. foreign assistance funded by or through the State Department and U.S. Agency for International Development (USAID) to allow the Trump administration to review if the money puts "America First."

On Sunday, the State Department released a statement about falling in step with President Donald Trump’s executive order to reevaluate and realign foreign aid from the U.S.

"Consistent with President Trump’s Executive Order on Reevaluating and Realigning United States Foreign Aid, Secretary [Marco] Rubio has paused all U.S. foreign assistance funded by or through the State Department and U.S. Agency for International Development (USAID) for review," the statement read. "He is initiating a review of all foreign assistance programs to ensure they are efficient and consistent with U.S. foreign policy under the America First agenda. President Trump stated clearly that the United States is no longer going to blindly dole out money with no return for the American people."

The statement continued, saying the review and alignment of foreign assistance on behalf of taxpayers is a "moral imperative," adding that Rubio is proud to protect America’s investment "with a deliberate and judicious review" of how the money is spent on aiding foreign countries overseas.

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"The implementation of this Executive Order and the Secretary’s direction furthers that mission," the statement read. "As Secretary of State Marco Rubio has said, ‘Every dollar we spend, every program we fund, and every policy we pursue must be justified with the answer to three simple questions: Does it make America safer? Does it make America stronger? Does it make America more prosperous?’"

The announcement comes after the Trump administration ordered staffers with USAID to stop providing foreign aid worldwide or face "disciplinary action" for not complying.

Reuters reported that the Trump administration sent a sharply-worded memo to more than 10,000 staff members at USAID on Saturday, offering a "stop-work" directive from Friday that put a freeze on U.S. foreign aid around the world.

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The wire service reviewed the memo and said it laid out expectations for the workforce on how to achieve Trump’s goals to put "America First."

"We have a responsibility to support the President in achieving his vision," Ken Jackson, assistant to the administrator for management and resources wrote in the internal memo, titled "Message and Expectation to the Workforce."

"The President has given us a tremendous opportunity to transform the way we approach foreign assistance for decades to come," the memo added. Reuters reported that it confirmed the authenticity of the memo with several sources.

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Trump ordered a 90-day pause in foreign aid just hours after taking office, to review if the funding was in line with his foreign policy priorities.

On Friday, the State Department issued a pause on aid worldwide.

The U.S. is the largest donor of aid globally. During fiscal year 2023, the U.S. dispersed $72 billion in assistance. It also provided 42% of all humanitarian aid tracked by the United Nations in 2024.

Fox News Digital has reached out to USAID for comment.

Reuters contributed to this report.

Secretary of State Marco Rubio told Chinese Foreign Minister and Director of the CCP Central Foreign Affairs Commission Wang Yi that the Trump administration will put the "American people first" and advance U.S. interests in its relationship with China, according to a readout of the call from spokesperson Tammy Bruce. 

The meeting was the first between Rubio and Wang since the former Florida senator was unanimously approved by the Senate this week to become President Donald Trump’s first Cabinet official following Monday's inauguration. 

"The Secretary also stressed the United States’ commitment to our allies in the region and serious concern over China’s coercive actions against Taiwan and in the South China Sea," Bruce said. "The Secretary also discussed other issues of bilateral, regional, and global importance with his Chinese counterpart." 

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Wang told Rubio during the call that he hoped he would "conduct" himself well and "play a constructive role in the future of the Chinese and American people and in world peace and stability." 

He added that Trump and Chinese President Xi Jinping had already set the tone for U.S.-Chinese relations. 

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"The teams of both sides should implement the important consensus of the two heads of state, maintain communication, manage differences, expand cooperation, promote the stable, healthy and sustainable development of China-U.S. relations, and find the right way for China and the United States to get along in the new era," Wang said.

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Trump has threatened China with 10% tariffs on imports over its role in fentanyl trafficking, starting as early as Feb. 1, and Rubio called the country the gravest threat to the U.S. during his confirmation hearing. 

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Trump n Thursday told the World Economic Forum virtually that he and Xi have "always had a great relationship," and all his administration wants is "fairness. We just want a level playing field."

In one of the first moves of his administration, President Donald Trump signed an executive order taking drastic steps to crack down on the violent Venezuelan migrant gang "Tren de Aragua," which has been terrorizing American cities in recent months.

Also known as "TdA," Tren de Aragua is a Venezuelan criminal group present in over a dozen U.S. cities. The group has ties to the socialist Venezuelan dictator Nicolás Maduro and according to experts, is being used as a tool of asymmetric warfare to sow chaos and discord in the U.S.

Jose Gustavo Arocha, a former high-ranking Venezuelan military official and senior fellow at the U.S.-based Center for a Secure Free Society, told Fox News Digital that Trump’s order was an "extraordinary move" that is the "first good step in the route to neutralize TdA."

The order – which is titled "Designating Cartels And Other Organizations As Foreign Terrorist Organizations And Specially Designated Global Terrorists" – instructs newly confirmed Secretary of State Marco Rubio to move to designate Tren de Aragua, as well as Mexican gang MS-13 and other migrant gangs as "foreign terrorist organizations."

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A foreign terrorist designation expands the government’s ability to crack down on criminal groups operating in the U.S., allowing all government agencies, including the Department of the Treasury, to target that group from every angle.  

The order states that these groups "present an unusual and extraordinary threat to the national security, foreign policy, and economy of the United States," and invokes the International Emergency Economic Powers Act (IEEP) to declare a national emergency to "deal with those threats."

"It is the policy of the United States to ensure the total elimination of these organizations’ presence in the United States and their ability to threaten the territory, safety, and security of the United States through their extraterritorial command-and-control structures, thereby protecting the American people and the territorial integrity of the United States," reads the order.

The order gives Rubio 14 days to make policy recommendations – in consultation with the secretaries of the Treasury and Homeland Security as well as the U.S. attorney general and director of National Intelligence – to make a recommendation regarding the designation of TdA, MS-13 and any other group as a foreign terrorist organization.

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According to Arocha, this move could spell the beginning of the end for TdA’s reign of terror in the United States.

"This executive order that Trump signed is perfect to neutralize unconventional tools that were made by the Venezuela regime," he said. "The TdA is an asymmetrical and unconventional tool to harm the United States, [and] not only the United States, all the region … [so] you have to use unconventional tools, too."

Joseph Humire, executive director of the Center for a Secure Free Society who in 2024 authored a report on how to dismantle TdA, explained to Fox News Digital that designating these groups as foreign terrorist organizations places them "at the highest level" of U.S. national security interest, meaning their funding and any organizations enabling them can be targeted as well.

"Trump just put all of them on notice," said Humire. "This said: ‘We know you're here; we know you're up to no good and we're going to come after you.'"

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"Now critics may say, well, he's going to create a war on terror or drugs, and it's really a reaction of fear. They say: 'Oh, you know, these guys are so dangerous.' And what you know about criminality, whether it's terrorism or any kind of criminality, is that they only respond to strength. They prey on fear. If they think you're scared to attack you more," he said. "So, by showing this strength, it's the first action of deterrence."

In addition to sending a message of strength, Humire said the executive order signals that there will be "meaningful action taking place really, really soon to start to arrest and dismantle" TdA’s presence in the U.S.

Andrew Arthur, a law and policy expert at the Center for Immigration Studies, told Fox News Digital that one of the most important aspects of designating TdA a foreign terrorist organization is enabling the U.S. government to target TdA’s funding, which he said can essentially "bleed them dry."

CLICK HERE FOR MORE IMMIGRATION COVERAGE

"Money is the lifeblood of these organizations," he said. "It's really the funding element of all this that is crucial to going after a terrorist organization, because if you cut them off from the money, they're not going to be able to pay people. They're not going to be able to pay bribes to corrupt officials, they are not going to be able to pay their foot soldiers, are not going to be able to buy the big guns and the things that they used to operate."

"It's not just the guy with the AK-47 or the guy with the IED that's a terrorist. It's all those people that helped to make that possible," he went on. "So, when you designate them as terrorist organizations, in addition to going after the keepers or the kingpins of these organizations and the various foot soldiers that they employ, you can also go after the individuals who provide material support."

Secretary of State Marco Rubio got into a tense exchange with NBC's "Today" show on Tuesday after one of the network's hosts repeatedly asked him about President Trump's sweeping Jan. 6 pardons.

Following a quick introduction, NBC immediately played a 2021 clip of Rubio condemning the Jan. 6 attack on the Capitol.

"Vladimir Putin loved everything that happened here today because what happened is better than anything he could have ever come up with to make us look like we're falling apart," he said at the time.

After the video ended, NBC host Craig Melvin asked Rubio what message the pardons send to the rest of the world.

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Rubio replied that he would not "engage in domestic political debates" with the media and could not in his role as the head of the State Department.

"I hope you guys all understand that my days – at least in the time at the Department of State – of engaging in domestic politics will be put aside as I focus on the affairs the United States has around the world and the engagements we have to have to make our country a safer, stronger, more prosperous place," he later added.

Melvin again pressed Rubio on the pardons – questioning if Trump's decision would give the now freed defendants incentive to foment a future attack.

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"I think it's unfortunate, you know, our first engagement as I agree to come on this morning with you. I'm going to be working on foreign policy issues, and you want to revisit these issues that are going on in domestic politics. I'm just – it's not going to happen," Rubio said. "If you have questions for me about foreign policy and engaging in the world, I'd be happy to talk to you about those."

Rubio similarly stressed his "singular" focus on foreign policy when asked about the pardons on "CBS Mornings" and ABC's "Good Morning America."

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Trump pardoned nearly all Jan. 6 defendants on Monday night after promising at his inaugural parade to sign an executive order on the matter.

Sitting at the Resolute desk in the Oval Office, Trump signed off on releasing more than 1,500 charged with crimes stemming from the Jan. 6, 2021, attack at the U.S. Capitol. The order requires the Federal Bureau of Prisons to act immediately on receipt of the pardons.

Fox News' Diana Stancy and Jamie Joseph contributed to this report.

Florida Sen. Marco Rubio was confirmed unanimously by the Senate to be the next secretary of state, making him the first of President Trump's Cabinet picks to receive congressional approval.

Rubio, a senator since 2011, was confirmed during a floor vote by the full Senate Monday night, several hours after Trump took his oath of office earlier in the day. The full Senate floor vote occurred following a separate vote by the Senate Foreign Relations Committee, which also voted unanimously in favor of Rubio's nomination Monday.  

Rubio enters his role as secretary of state with a strong foreign policy background as a longtime member of the Senate's Foreign Relations and Intelligence Committees. He is also a first-generation Cuban American.

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His road to confirmation has been less controversial than many of Trump's other Cabinet picks. At Rubio's first confirmation hearing last week in front of the Foreign Relations Committee, the committee's top-ranking Democrat, Sen. Jeanne Shaheen of New Hampshire, said she thought Rubio possessed "the skills" and is "well-qualified" to serve as the next secretary of state. She echoed this sentiment Monday evening as well before the full Senate vote.

"I've had a good working relationship with Sen. Rubio for many years, and I was very impressed during his hearing by his grasp of policy," Shaheen said Monday evening. "While we may not always agree, I believe he has the skills, knowledge and qualifications to be secretary of state."

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Rubio expressed during his initial confirmation hearing last week that under Trump the State Department's "top priority" will be to put America first. 

"This will not be easy," Rubio said. "And it will be impossible without a strong and a confident America that engages in the world, putting our core national interests, once again, above all else."

Rubio will face some major challenges heading into his new role, notably the ongoing Russian invasion of Ukraine and the war between Israel and Hamas in Gaza.

Rubio described the fighting between Ukraine and Russia as a "stalemate" that "has to end" during his confirmation hearing last week, adding that under Trump's proposed peace deal both countries will have to make "concessions." Meanwhile, despite Trump's past criticisms of the North Atlantic Treaty Organization (NATO), Rubio called the alliance "very important" and insisted that Trump was also a NATO supporter.

On Gaza, Rubio supported Israel's actions to defend itself against Hamas but stopped short of indicating one way or the other if he thought Israel's annexation of parts of the West Bank was something he supported. 

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"The idea would be that there not be conflict and the people could live side-by-side with one another without being in conflict and with the ability to pursue prosperity," Rubio said. "Sadly and unfortunately the conditions for that to exist have not been in place for a substantial period of time."

Rubio also repeatedly singled out China during his remarks in front of the Senate Foreign Relations Committee last week. "We welcomed the Chinese Communist Party into this global order. And they took advantage of all its benefits. But they ignored all its obligations and responsibilities," Rubio posited at his hearing. "Instead, they have lied, cheated, hacked and stolen their way to global superpower status, at our expense."

While Rubio did not face significant opposition to his confirmation, some Trump-aligned Republicans have expressed disdain over Rubio's willingness to certify the results of the 2020 election that Trump alleged was "stolen" from him. Sen. Rand Paul, R-Ky., who has been an outspoken supporter of less U.S. intervention, also questioned Rubio's hawkish stance on American intervention amid his confirmation to be secretary of state.

Florida Attorney General Ashley Moody, who is slated to become a U.S. senator, is calling for an audit of the Federal Reserve, pledging to vocally oppose government spending, and declaring that she will fight to bolster the border and remove individuals who enter the U.S. illegally.

With Sen. Marco Rubio, R-Fla., poised to soon leave office to serve as Secretary of State in the new Trump administration, Florida Gov. Ron DeSantis announced Moody as his pick to replace Rubio in the U.S. Senate. 

And with even some Democrats planning to support confirmation, Rubio is likely to sail through the confirmation vote.

"Here's a priority of mine in the Senate: our inflation has been fueled by the Federal Reserve. We must audit the Fed!" Moody declared in a post on X.

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"As Florida’s next U.S. Senator, I will work tirelessly to reduce the bloat of Washington and speak out loudly against government spending," she noted in another post. "Like we've done in Florida, this country needs to cut spending and get fiscally responsible. I look forward to working with DOGE, and I will work hard to leave the next generation of our country on a much stronger financial footing."

When discussing her role in confirming judges and justices, she specifically mentioned Supreme Court Justices Clarence Thomas and Samuel Alito.

"As a former judge, I will take my role confirming judges and justices seriously to ensure that, like Justices Thomas and Alito, they share the values and concepts of law as our Founding Fathers understood them," she said in a tweet. "I will work through the Senate confirmation process to ensure those who get confirmed are strong nominees and know that it is their duty to interpret the Constitution as it is written."

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Sharing Moody's post, DeSantis called Alito and Thomas "the gold standard."

"In the U.S. Senate, I will support President @realDonaldTrump and fight for legislation that strengthens the border, builds the wall, and removes those who entered unlawfully," Moody noted in a tweet.

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DeSantis responded, declaring, "Make Illegal Immigration Illegal Again."

Gov. Ron DeSantis, R-Fla., revealed on Thursday who he plans to appoint to the Senate once Sen. Marco Rubio, R-Fla., resigns, as he is expected to be confirmed to be President-elect Donald Trump's Secretary of State after his inauguration. 

The governor selected Florida Attorney General Ashley Moody to be the next senator. 

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Moody has been a key ally of DeSantis in the state and worked in tandem with him to facilitate his agenda as governor. 

During his Thursday announcement, DeSantis said "So this is something that I thought about long and hard. We did a lot of research. We got a number of great candidates throughout the state of Florida, and many of them, I think, could have done a good job. But the final criteria I used was because you can say all those things and say you stand for it—I wanted somebody with a demonstrated record of delivering results on those important issues. Talk is cheap."

"We need people that have demonstrated fidelity to these principles with their actions. So that is why today I'm proud to announce that I am selecting our Attorney General, Ashley Moody, to serve as our next U.S. Senator," he told attendees. 

Moody accepted the challenge and thanked the governor for choosing her. "Thank you so much. I will bring the same persistence and passion and tenacity as a United States Senator that I have brought as Florida's Attorney General," she said.

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"If you have worked with me and fought with me over the last six years, you know, I don't think of this as a job. I think of it as a calling," she explained. 

When asked about potentially taking on the role on "Fox and Friends First" in November, Moody previously said, "I have my hands full here as attorney general, and I'm incredibly focused on this job, working on behalf of Floridians, making sure I'm protecting the autonomy of the state and pushing Washington out of our business and holding them accountable. Of course, I love … being in leadership, working with President Trump, working with Governor DeSantis. And I hope to continue working on behalf of Floridians."

Initially, Trump and Sens. Katie Britt, R-Ala., and Rick Scott, R-Fla., endorsed Trump's daughter-in-law and former RNC Co-Chair Lara Trump to succeed Rubio. However, she later withdrew her name from consideration. 

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"After an incredible amount of thought, contemplation, and encouragement from so many, I have decided to remove my name from consideration for the United States Senate," she wrote on X. 

Following Thursday's announcement, Scott congratulated Moody on X. "I welcome @AGAshleyMoody to the United States Senate! Ashley has done an incredible job fighting for Floridians and keeping our communities safe as Attorney General. I have no doubt she will do an incredible job as senator!" he said. 

DeSantis added on Thursday that he expects to appoint Moody to the Senate the afternoon of January 20, after Trump is sworn in to office. 

"We anticipate Senator Rubio to get confirmed very quickly after the inauguration of the 47th president, President Trump," he said. 

He further thanked Rubio for his service as a senator. "I want to thank Senator Rubio for his service in the United States Senate. I think he will serve the country ably as Secretary of State and, we need it because, the last four years has been a total disaster, under the Biden-Harris administration," the governor said.